May 2009 - Publication of Baker PS, Brown GC.
Retina Service, Wills Eye Institute, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
Stem cell transplants can survive, migrate, differentiate and integrate within the retina.
Stem cells from various stages of development have been used in these experiments, including embryonic stem cells, neural stem cells, mesenchymal stem cells in the retina, and adult stem cells from the ciliary margin.
These transplants have shown evidence of reconnection and synaptic visual recovery in both animal and human studies.
Still, much work must be done to achieve higher operating income and retinal neurons.
ABSTRACT: Despite many obstacles, stem cell therapies are promising therapies to restore vision in patients with retinal disease.